...if you don't take the time to research your prospects.
As a translation company, we keep receiving large amounts of very generic e-mails from translators, all addressed to "Dear Sir or Madam" and variations on the same theme, including "Dear Ladies and Gentlemen", "Hello Dear" (?), "Good Day", "Hi there", "Hello", Hello Sir/Madam", and so on.
The following is just a part of today's crop:
If you are looking for new clients, take the time to research your prospects, and customize your marketing for each of your prospects. You'll have much greater success.
If, on the other hand, you insist in sending out generic e-mails in bulk, remember, there is a term for that: it's called "spam" and it is actually forbidden in many countries.